1591 - Samoothiri allowed the Portuguese to build a factory at Kozhikkode. He even laid the foundation of their church granting them necessary ground and building materials. His commanders like Kunjali Marakkar who were sworn enemies of the Portuguese were ignored again. Kunjali began to distance himself from Samoothiri.
 

1598 - Samoothiri joined with the Portuguese and fought his own Commander, Kunjali Marakkar. Kunjali surrendered to Samoothiri, and Samoothiri handed him over to the Portuguese, who killed him. Thus ended a glorious era of unflinching resistance from the Marakkar family to the Portuguese in Kerala.
 

1604 - The Dutch came and concluded a treaty with the Samoothiri, by virtue of which they were permitted to trade at Kozhikkode and Ponnani and to build forts in these places for their protection.
 

1646 - The reigning branch of Kochi Raja became extinct and adoptions were made both from the dispossessed branch and a collateral branch living at Palluruthy. Between these two branches family feud broke out.